Scientific Support

Scientific Support:

1.  Grimmett, A., Sillence, M.N. 2005, Review: Calmatives for the excitable horse: A review of L-tryptophan. The Veterinary Journal, 170 pp 24-32

2.  Marine Peptides: Bioactivities and Applications; Randy Chi Fai Cheung , Tzi Bun Ng  and Jack Ho Wong, School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong, China, April 2015.
Publication Website –

3.  Bagshaw, C.S., Ralston, S.L., Fisher, H., 1994. Behavioural and physiological effect of orally administered tryptophan on horses subjected to acute isolation stress. Applied Animal Behaviour Science 40, 1-12.

4.  Bellisle, F., Blundell, J.E., Fantino, M., Fern, E., Fletcher, R.J., Lambert, J., Roberfroid, M., Specter, S., Westenhofer, J., Westerp­ Plantenga, M.S., 1998. Functional food science and behaviour and psychological functions. British Journal of Nutrition 80, S173-S193.

5.  REGULATION OF SEROTONIN SYNTHESIS MARGARET C. BOADLE-BIBER Department of Physiology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298, U.S.A.

6.  Bernet, F., Montel, V., Noel, B., Dukpouy, J. P. (2000). Diazepam-like effects of a fish protein hydrolysate (Gabolysat PC60) on stress responsiveness of the rat pituitary-adrenal system and sympathoadrenal activity. Psychopharmacol., 149(1), 34-40.

7.  Noble GK1, Brockwell YM, Munn KJ, Harris PA, Davidson HP, Li X, Zhang D, Sillence MN. Equine Vet J. Effects of a commercial dose of L-tryptophan on plasma tryptophan concentrations and behaviour in horses. Equine Vet J. 2008 Jan;40(1):51-6.

8. Landsberg et al. 2015. Journal of Veterinary Behaviour 10 (2015). Assessment of noise-induced fear and anxiety in dogs. Modification by a novel fish hydrolysate supplemented diet.

9. Kentucky Equine Research Staff. 2015. Calming Horse Supplements Tryptophan Research